Ebioschip Systems

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	Phone : Mail : Address : EBIOCHIP SYSTEMS GMBH Fraunhoferstrasse 1 Itzehoe Germany Web : http://www.ebiochip.com

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	Electrical bio sensor arrays for analyses of harmful micro organisms and microbial toxins EBIOSENSE 2005 - 2007 Subjects : Medicine, Health, Biotechnology, Life Sciences Other Indexes:clinical,electric biochip,environmental,food diagnostics,protein and nucleic acid based arrays Contract type : Specific Targeted Innovation Project Participants : KUNGL. TEKNISKA HOGSKOLAN SVERIGE KUNGL. TEKNISKA HOGSKOLAN Other DEPARTMENT OF BIOTECHNOLOGY Valhallavagen 60 SVERIGE EBIOSCHIP SYSTEMS GMBH DEUTSCHLAND EBIOSCHIP SYSTEMS GMBH Industry EBIOCHIP SYSTEMS GMBH Fraunhoferstrasse 1 DEUTSCHLAND UNIVERSITY OF OULU SUOMI/FINLAND UNIVERSITY OF OULU Other,Education DEPARTMENT OF PROCESS AND ENVIRONMENTAL ENGINEERING/LABORATORY OF BIOPROCESS ENGINEERING PO Box 8000 Linnanmaa SUOMI/FINLAND SCANBEC OY SUOMI/FINLAND SCANBEC OY Industry SCANBEC OY PL19 Kiviharjuntie 11 SUOMI/FINLAND FRAUNHOFER GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V DEUTSCHLAND FRAUNHOFER GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V Other FRAUNHOFER INSTITUT FÜR SILIZIUM TECHNOLOGIE Hansastrasse 27 C DEUTSCHLAND ERNST MORITZ ARNDT UNIVERSITÄT DEUTSCHLAND ERNST MORITZ ARNDT UNIVERSITÄT Other INSTITUTE OF MICROBIOLOGY Domstraße 11 DEUTSCHLAND UNIVERSITY OF GDANSK POLSKA UNIVERSITY OF GDANSK Other DEPARTMENT OF MOLECULAR BIOLOGY Bazynskiego 1A POLSKA PLANT RESEARCH INTERNATIONAL B.V. NEDERLAND PLANT RESEARCH INTERNATIONAL B.V. Research BIOINTERACTIONS AND PLANT HEALTH Droevendaalsesteeg 1 NEDERLAND CENTRE DE RECHERCHE ET D'ÉTUDE POUR L'ALIMENTATION' FRANCE CENTRE DE RECHERCHE ET D'ÉTUDE POUR L'ALIMENTATION' Other 199 rue raymond Losserand FRANCE RAISIO BENECOL LTD SUOMI/FINLAND RAISIO BENECOL LTD Industry PO Box 101 Raisionkaari 60 SUOMI/FINLAND MICRO ELECTRONICS CONSULTANTS DR. INGO HUSSLA DEUTSCHLAND MICRO ELECTRONICS CONSULTANTS DR. INGO HUSSLA Other Fraunhoferstrasse. 3 DEUTSCHLAND SCANBEC GMBH DEUTSCHLAND SCANBEC GMBH Industry SCANBEC GMBH Weinbergweg 23 DEUTSCHLAND RAISIO BENECOL Finland RAISIO BENECOL Industry PO Box 101 Raisionkaari 60 Finland SCANBEC Finland SCANBEC Industry SCANBEC OY PL19 Kiviharjuntie 11 Finland EBIOSCHIP SYSTEMS Germany EBIOSCHIP SYSTEMS Industry EBIOCHIP SYSTEMS GMBH Fraunhoferstrasse 1 Germany SCANBEC Germany SCANBEC Industry SCANBEC GMBH Weinbergweg 23 Germany Hide objective Main objective is to develop an advanced platform for analysis of harmful micro organisms and/or their toxic products. The goal will be reached by integration of the data on genomes and proteomes available through bioinformatics and advanced silicon and m icrosystem technology. The platform, based on ambitious electric biochip arrays, will enable parallel and simultaneous identification and quantification of specific nucleic acids, microbial proteins and toxic microbial products. The targets are recognized and captured by DNA probes or antibodies on the electrochemical transducer surface, that are arrays of nm-sized interdigital gold electrodes The captured analyte molecules are labelled with an enzyme that produces an electroactive product thus generatin g an electric current that corresponds to the concentration of the target analyte in the sample. All application developing partners use this platform and same electrical read out instrumentation but they implement their special expertise into developmen t of specific innovative chip arrays. The DNA-and protein-arrays require different and specific procedures for chip loading of the recognition elements, and for detection. The equipment's will be portable devices and are furnished with disposable chips. The technique will be generic but the applications in the project are selected analyses of food and water born harmful micro organisms and microbial toxins: 1) Shiga toxin producing Escherichia coli (STEG, ETEC, EHEC etc); 2) Salmonella enteriditis 3) pa thogenic strains of Bacillus cereus, 4) pathogenic Staphylococcus strains that cause food poisoning and infections, 5) Legionella responsible for the Legionnaire's disease distributed via water, and 6) Mycotoxins. The diagnostic equipment is evaluated fo r functionality in different exploratory prototypes by a large industrial partner and a specialised SME, assessing the quality management issues for pharma/food/evironmental industry.' Source : cordis